An important event for the staff of International research and production holding "Phytochemistry" is a visit on August 21, 2014 of the deputies of the Majilis of the Parliament of the Republic of Kazakhstan (S. Kanaev, M. Pshembaev, M. Tinikeev, S. Aimbetov, T. Kenzhin) and a visit on August 27, 2014 of Akim of Karaganda region N.K. Abdibekov to the International research and production holding "Phytochemistry" and Karaganda pharmaceutical plant.

During the working visit the deputies of the Majilis of the Parliament of RK and Akim of Karaganda region N.K. Abdibekov acquainted themselves with the work of holding "Phytochemistry" on applying international standards in pharmaceutical manufacturing. Opinions exchange on issues of transition of domestic pharmaceutical industry to international GMP standards and development of the bank of standard samples of medicinal and biologically active compounds.

By results of the visit, the deputies of the Majilis of the Parliament of RK and Akim of Karaganda region approved scientific production activity of the holding company, drew attention to the need of strengthening of the fight against medicines adulteration:

-to brisk up the work of the Republican data bank, as the presence of domestic standard samples of drug substances will help to accelerate the implementation of the international GMP standards into domestic pharmaceutical industry.

-to prepare and accept appropriate normative legal acts on scientific-technical Program "Development and organization of new domestic medicines production in accordance with GMP standards".

-to supply regional laboratories of the National center of examination of drugs, medical devices and medical equipment with domestic standard samples of drugs for quality control of medicines at state registration and certification.

The deputies of the Majilis of the Parliament of RK sent a deputy inquiry addressed to the Prime Minister of the Republic of Kazakhstan K.K. Masimov dated September 25, 2014. No. DZ-269, to which the Prime Minister of RK Karim Masimov gave orders dated October 20, 2014 No. 20-11/4722.

The Ministry of Education and Science of the Republic of Kazakhstan (hereinafter-the Ministry) in order to fulfil the direction of the Prime Minister of RK Karim Masimov dated October 20, 2014 No. 20-11/4722 on the issue of biologically active compounds conducted a working meeting on October 30, 2014 with the participation of the representatives of the Ministries of Healthcare and Social Development (hereinafter-MHSD), investment and development (hereinafter-MID), JSC "IRPH "Phytochemistry", Private Institution "Life Sciences Center" AEO "Nazarbayev University", Republican State Enterprise "National center of examination of drugs, medical devices and medical equipment".

Following the meeting, the action team developed proposals to issues raised by the deputies of the Majilis of the Parliament of the Republic of Kazakhstan.

Regarding the work activation of the Republican bank of biologically active compounds.

According to information of MHSD standard samples play an important role in ensuring the quality of medicines throughout their life-cycle, from drug development to monitoring medicines quality on the country market.

The Republic of Kazakhstan in the field of pharmacy headed for the harmonization with the European community and this will require the establishment of a system of pharmacopoeial standard samples that meet the requirements of the appropriate pharmaceutical GMP practices and of the international pharmacopoeias practice.

Currently the Republic of Kazakhstan is a member of the American Pharmacopoeia, the European Pharmacopoeia observer; an official permission of usage of British pharmacopoeia materials is obtained. This standing allowed to harmonize national pharmacopoeia standards with international demands, increase requirements to quality and safety of medicines, to deepen the policy in the field of quality of medicines.

The most important step is the establishment of the official standard samples of the State pharmacopoeia of the Republic of Kazakhstan (SP RK), which is possible with high-level requirements of the national pharmacopoeia.

Within the framework of the state program "Salamatty Kazakhstan" is completed the development of volume III, SP RK, updating of previous volumes is being carried out.

Creation of a system of pharmacopoeial standard samples requires not only high scientific potential, but rather large financial expenditures on its creation and maintenance.

Regarding the preparation of relevant normative legal acts on scientific-technical Program "Development and organization of new domestic medicines production in accordance with GMP standards".

IRPH "Phytochemistry" prepared and presented the draft project of the program "Development of new pharmacological substances compounds of original medicines and their standard samples" for the contest within the framework of program-targeted financing of scientific researches in 2015-2017 for the Committee of Science of the Ministry of Education and Science of the Republic of Kazakhstan. The main goal of this program is strengthening of the fight against medicines adulteration and work activation of the Republican Bank of biologically active compounds and Republican Bank of standard samples and impurities of drug substances.

According to the Law of the Republic of Kazakhstan "On science" program-targeted financing is directed to fulfil strategically important state tasks and is carried out on a competitive basis or by decision of the Government of the Republic of Kazakhstan out of competitive procedures.

The results of the contest will be posted on the Internet resources of the Ministry.

Regarding the creation of the integrated system of biological and pharmacological screening of new chemical compounds, both natural and synthetic origin.

In terms of organization of integrated system of biological and pharmacological screening of new compounds it is necessary to create a Centre of pharmacology as a single center of searching for drug substances of natural and synthetic origin.

According to information of the Private Institution "Life Sciences Center" AEO "Nazarbayev University" under the Strategic development plan of Private Institution "Life Sciences Center" for 2014-2016, approved by the journals of the Governing board of AEO "Nazarbayev University" dated 13.12.2013, No. 13.12.13, at the base of Life Sciences Center is planned creating of an institutional foundation in the form of a Center or an Institute of pharmacology and clinical pharmacology in 2016.

Regarding the supplying of the regional laboratories of the Republican State Enterprise on the base of economic management "National center of examination of drugs, medical devices and medical equipment" (hereinafter - the National center).

According to information of MHSD for supplying of regional laboratories of the National centre with domestic standard samples of drugs for quality control of medicines at state registration and evaluation of safety and quality of registered medicines in accordance with international standards should be used pharmacopoeial standard samples.

Today at the National center undergo an examination 14 types of standard samples of biological active substances (BAS), developed by IRPH "Phytochemistry" for including in the State Pharmacopoeia of the Republic of Kazakhstan (SP RK).

According to the Plan of the development of SP RK it is planned in 2015 including into the updated volume 1 of SP RK of standard samples of BAS developed by IRPH "Phytochemistry" for further use in quality control of drugs at state registration and evaluation of safety and quality.

Besides, according to the information of MID in order to update their laboratories with the necessary equipment for production of standard samples of drugs IRPH "Phytochemistry" can participate in the program "Productivity - 2020" whose objectives are modernization (technical re-equipment) of existing and creation of new competitive industries, as well as service support of business entities..